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KMID : 0383819860330040196
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Tuberculosis and Respiratory Diseases
1986 Volume.33 No. 4 p.196 ~ p.201
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Natural Killer Cell Mediated Cytotoxicitd and Antibody-Dependent Cell Mediated Cytotoxicity in Tuberculosis Patients (I)
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김성규/Sung Kyu Kim
오광제/안철민/윤여운/손희영/김기호/최인홍/윤정구/Kwong Je Oh/Chul Min Ahn/Yoe Wun Yoon/Hee Young Sohn/Ki Ho Kim/In Hong Choi/Jung Koo Yoon
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Abstract
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Cellular immunity is predominantly involved in pulmonary tuberculosis. Natural Killer
(NK) cells and Killer (NK) cells play an important role in cellular immunity.
Natural Killer cell mediated cytotoxicity (NKMC) was studied in 51 patients with
active tuberculosis and 39 healthy controls. Antibodydependent cell mediated cytotoxicity
(ADCC) was studied in 41 patients with active tuberculosis and 15 healthy controls.
There were no differences between the patients and the controls in NKMC and
ADCC. There were no significant differences in the mean values of NKMC and ADCC
among the minimal, moderately advanced and far advanced pulmonary tuberculosis
patients.
We conclude that NK and K cells are not of prime importance in the body's defence
against tuberculosis.
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KEYWORD
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